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Robust inference with the knockoff filter

Presented by: 
Rina Foygel Barber University of Chicago
Monday 15th January 2018 - 11:10 to 11:55
INI Seminar Room 1
In this talk, I will present ongoing work on the knockoff filter for inference in regression. In a high-dimensional model selection problem, we would like to select relevant features without too many false positives. The knockoff filter provides a tool for model selection by creating knockoff copies of each feature, testing the model selection algorithm for its ability to distinguish true from false covariates to control the false positives. In practice, the modeling assumptions that underlie the construction of the knockoffs may be violated, as we cannot know the exact dependence structure between the various features. Our ongoing work aims to determine and improve the robustness properties of the knockoff framework in this setting. We find that when knockoff features are constructed using estimated feature distributions whose errors are small in a KL divergence type measure, the knockoff filter provably controls the false discovery rate at only a slightly higher level. This work is joint with Emmanuel Candès and Richard Samworth.
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University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons